在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4),partial

In Stock
  • 中文名稱:
    人ITIH4重組蛋白
  • 貨號:
    CSB-YP617923HU
  • 說明書:
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP617923HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) ITIH4.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP617923HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) ITIH4.
    • The purity of ITIH4 was greater than 90% as determined by SEC-HPLC
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
    Greater than 90% as determined by SEC-HPLC.
  • 基因名:
  • Uniprot No.:
  • 別名:
    35 kDa inter-alpha-trypsin inhibitor heavy chain H4; gp120; H4P; IHRP; Inter-alpha-inhibitor heavy chain 4; Inter-alpha-trypsin inhibitor family heavy chain-related protein; Inter-alpha-trypsin inhibitor heavy chain H4; inter-alpha-trypsin inhibitor, heavy chain-like, 1; ITI heavy chain H4; ITI-HC4; ITIH4; ITIH4_HUMAN; ITIHL1; OTTHUMP00000197120; OTTHUMP00000197121; OTTHUMP00000213834; OTTHUMP00000213869; PK-120; PK120; Plasma kallikrein sensitive glycoprotein 120; PRO1851
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Yeast
  • 分子量:
    28.9 kDa
  • 表達區域:
    689-930aa
  • 氨基酸序列
    RLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The fusion tag N-terminal 6xHis tag gene was added to the gene sequence corresponding to the yeast of the human ITIH4 protein to form the recombinant DNA. The recombinant DNA was cloned into the expression vector and then transfected into the yeast cells for expression. Following purification, the product is the recombinant human ITIH4 protein carrying N-terminal 6xHis tag. The SDS-PAGE assessed the purity of this recombinant ITIH4 protein up to 85%. It had an apparent molecular weight of approximately 30 kDa.

    ITIH4 is a gene encoding a protein called inter-alpha-trypsin inhibitor heavy chain H4 in human and belongs to ITIH family, which was associated with inflammation and carcinogenesis. This gene is located in a cluster of related inter alpha trypsin inhibitor genes on chromosome 14. The protein encoded by this gene is a 120 kDa acute-phase glycoprotein produced primarily in the liver. ITIH4 is involved in liver development and stabilization of the extracellular matrix (ECM), and its expression is altered in liver disease.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
  • 基因功能參考文獻:
    1. Low ITIH4 expression is associated with Hepatocellular Carcinoma. PMID: 28828637
    2. this report has further supported for associations of genetic variants in the ITIH4 and CALN1 genes with schizophrenia and provided the first evidence that the variants regulate ITIH4 AND CALN1 expression in the dorsolateral prefrontal cortex PMID: 26991396
    3. ITIH4 peptide isoform as a preterm birth biomarker and its associated SNP implications PMID: 26408095
    4. Serum ITIH4 may be a PM10-specific biomarker in COPD and may be related to inflammation. PMID: 25977605
    5. Four novel body mass index-associated loci near the KCNQ1(rs2237892), ALDH2/MYL2 (rs671, rs12229654), ITIH4 (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations. PMID: 24861553
    6. Worse survival among HCC patients with low ITIH4. PMID: 24836184
    7. Isoform-specific ITIH4 glycosylation and utilization of O-glycosylation sites on ITIH4 differs between cell lines and serum. PMID: 24884609
    8. Expression of the 85 kDa ITIH4 was substantial in amyotrophic lateral sclerosis compared with controls or patients with muscular dystrophy, Alzheimer diseases, or Parkinson diseases PMID: 23436019
    9. A truncated fragment of inter-alpha-trypsin inhibitor heavy chain 4 was the sole protein found to be significantly enhanced in the prostate cancer patients compared to the controls. PMID: 23417432
    10. Findings suggest that ITI-H4 expression may be used as a biomarker, which could facilitate the development of novel diagnostic and therapeutic tools. PMID: 21331437
    11. Genetic variation at ITIH4 locus is one of the likely candidate determinants for plasma cholesterol metabolisms PMID: 14661079
    12. ITIH4 and MTJ1 co-immunoprecipitate from total liver protein extracts and SANT domain of HTJ1 protects the ITIH4(588-930) recombinant fragment PMID: 16271702
    13. The inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) protein was significantly present more in interstial cystitis than controls PMID: 18455532
    14. ITIH4 is an anti-inflammatory protein, and suggests that further investigation into its potential use in the diagnosis and prognosis of acute ischemic stroke is warranted. PMID: 19263524

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    ITIH family
  • 組織特異性:
    Liver specific.
  • 數據庫鏈接:

    HGNC: 6169

    OMIM: 600564

    KEGG: hsa:3700

    STRING: 9606.ENSP00000266041

    UniGene: Hs.709406



主站蜘蛛池模板: 777天堂麻豆爱综合视频| 天堂а√中文最新版在线| 天堂а√中文最新版在线| 青青久久成人免费影院| 无遮挡边吃摸边吃奶边做| 影视先锋av资源噜噜| 无套内射视频囯产| 亚洲日产av中文字幕无码偷拍| 激情综合五月丁香亚洲| 日韩人妻无码免费视频一区二区三区 | 国产麻豆成人传媒免费观看| 中字幕人妻一区二区三区 | 欧美成人一卡二卡三卡四卡| 久久99精品国产99久久6不卡| 男女无遮挡激情视频| 久久精品a亚洲国产v高清不卡 | 亚洲高清成人aⅴ片| 国产美女视频免费观看网址| 日韩好精品视频你懂的| 四虎成人精品在永久免费| 在线观看国产精品电影| 色欲色香天天天综合网站| 久久综合婷婷丁香五月中文字幕| 日本大尺度吃奶呻吟视频| 天天做天天大爽天天爱| 国产精品星空无限传媒| 国产亚洲精品欧洲在线观看| 亚洲精品夜夜夜| 日本无遮挡真人祼交视频| 亚洲精品久久一区二区无卡| 欧洲人妻丰满av无码久久不卡| 欧美乱妇狂野欧美在线视频| 亚洲成色最大综合在线| 国产v在线最新观看视频| 国精无码欧精品亚洲一区| 欧美变态暴力牲交videos| 国产丰满乱子伦无码专区| 在线 v亚洲 v欧美v 专区| 乱女伦露脸对白在线播放| 亚洲红杏成在人线免费视频| 亚洲手机在线人成网站|